About your screen going psychedelic:

Using Mouse-Selected Region can be somewhat disconcerting. Once you invoke this capture method, the colors of various elements on your screen will invert as your mouse cursor passes over them (for example, pass your mouse over the image below). Nothing is wrong with your display, and it will return to normal after you complete your screen capture.

To use this capture method:

1. Select Mouse Selected Region.

   

2. Press the Print Screen key to activate the Region Selector, which inverts the colors of screen elements as your mouse cursor passes over them.
3. Move your mouse cursor to different areas of the screen and stop on a color-inverted area that you wish to print and/or capture.
   Note: While in this mode you can switch from one program to another, open windows, run programs, click on drop-down menus, etc. For example, if you want to capture or print a drop-down menu, you can click on "File" on a program's menu bar to open the drop-down menu and then position your mouse on the menu until the colors invert.
   
4. Press the Print Screen key to print and/or capture the color-inverted area. Note that the colors will not be inverted in the captured or printed image.

Notes about the Region Selector:

When you move your mouse cursor to an area of the screen that becomes inverted, a sub-selectable area may exist within that inverted area. An example of this is shown in Figures 1 and 2 below. In Windows Explorer, holding the mouse cursor over the area that contains the "Folders" title (Figure 1) inverts a particular area. Moving the mouse cursor down to the file list box (Figure 2) reveals a sub-selectable area. When you press the Print Screen key, only the area that is inverted will be printed and/or captured.